![]() Don't go back on it when you feel abnormalities in the vaginal area, but just stay off. I don't know about since January, but I think it is important to come off your Valtrex completely. 2) The taking of Valtrex could influence the result. If a follow-up test done at 6 months from the first one and run in parallel as the lab states is necessary, is still indeterminate, I think the feeling generally is that the test is really negative. It isn't completely clear why this happens, but there are a few reasons: 1) the patient has some other substance in their blood, perhaps a similar antibody, that is tripping the test just a little, but artificially. More often, the answer is clear, but about once every other month, we get an indeterminate result. It is not all that uncommon for someone who has an index value in this range to get back an indeterminate result. All tests with an index value of 1.1 to 3.5 get referred to western blot at UW. Hope you don't mind! We do lots of herpes testing in our clinic, about 20-25 tests per week. Handsfield wrote me about your post and said I could jump in here if I wanted to. Hi Seeking answers, This is Terri Warren from the herpes board. My questions are as follows: (1) does the fact that I have been taking 500 mg of Valtrex per day affect the validity of my test? (2) if so, how long should I stop taking Valtrex before being tested again? and (3) assuming Valtrex DOES NOT affect the validity of test results, should I still be tested again? Thank you. She said that it is possible that I am carrying the virus, but that I have not built up any antibodies that would produce a positive test result. My nurse practitioner told me that I do not have HSV II (or any other SDT) at this time and that the second test with the positive result must have been in error. Confirmatory tests were also administered, and both the initial and confirmatory tests were negative. I tested negative for every SDT, including HSV II. I was tested (blood serum) a third time last week and received my test results today. At the onset of these symptoms, I would increase my dosage to 1000 mg twice per day. I have, however, felt tingling every once and a while and a slight ache in my labia. I have never had an outbreak or any visible lesions. Ever since my diagnosis (February 10, 2010), I have taken 500 mg of Valtrex daily. Thus, I underwent a second HSV II blood serum test. However, my partner (with whom I ALWAYS used a condom) at the time also underwent HSV II testing after I told him about my symptoms and his results were positive. My doctors thought I had the flu and not herpes. I was tested for HSV II (blood serum test) and my results were negative. In January of this year, I had an enlarged lymph node in my groin and flu-like symptoms. Dear Doctor, I am a female in my mid-20s. ![]()
0 Comments
![]() So let's say I told you that this was 6, 2 and 9 as the lengths of those three sides, that would be considered scalene because none of these sides are equal to each other. Now comparing the three sides, we can identify scalene triangles. You can't have two 90 degree angles in a triangle because that will be a straight line and you couldn't form a triangle, so you know that in a right triangle your 90 degree angle will always always always be the largest angle. Next is a right-angle, excuse me a right triangle I got ahead of myself, a right triangle is identified by having one 90 degree angle. For an equilateral triangle however, you need three congruent sides an isosceles doesn't have that many. But an equilateral triangle is isosceles, the reason is isosceles you only need two congruent sides which an equilateral triangle does have. So we're going to call these, legs and an isosceles triangle is not an equilateral triangle. Moving on, if we have an isosceles triangle, which make sure you know how to spell this nothing drives Geometry teachers more insane than isosceles being spelt incorrectly, but an isosceles triangle has two sides that are congruent to each. Now just for triangles again this doesn't apply to quadrilaterals but just for triangles an equilateral triangle is the same as an equiangular triangle. ![]() ![]() ![]() If we talk about an Equiangular triangle, we're talking about a triangle where the three angles are all congruent to each other and since the sum of these angles is 180, 180 divided by 3 means that each of these angles measures 60 degrees.Īn equilateral triangle means that the three sides of your triangle are all congruent. There are many different types of triangles and some of them actually overlap. ![]() ![]() ![]() Looking for more tasty dog treats? Check out our Homemade Peanut Butter Dog Treats! Most dogs LOVE peanut butter (no Xylitol please), so you can’t go wrong with these yummy treats. These homemade dog biscuits also make a great gift for a dog lover! Pack them up in a cute dog-themed tin or simple bundle in a cellophane bag tied with ribbon. It resembles parsley but is highly toxic to dogs. Spring Parsley is a member of the carrot family. *Note: Be careful and use curly leaf parsley instead of ‘Spring Parsley’. In addition, it is often used in dog treats as a breath freshener. Parsley is a great source of antioxidants, vitamins, and is useful in soothing upset tummies and helping digestion. Parsley (the curly leaf variety) is also well known for providing health benefits to our pups. It may not sound appetizing, but it actually balances the other flavors in the dish and adds a depth of flavor. Most of us are familiar with parsley as a garnishment on our plates and sometimes used for seasoning our savory recipes.įor those that don’t know, parsley is a spice that has a slightly bitter flavor. One thing these homemade dog biscuits DO contain is parsley. ![]() This recipe is specifically without pumpkin and without peanut butter, which is something we have had requests for after sharing our other popular dog treat recipes that have them in. What’s notable in this recipe is there are two things we have left out. These homemade dog biscuits require very few ingredients and are super easy to make. Perhaps it is the bit of love thrown in?Īt any rate, pups quickly learn to recognize the smell of baking dog treats and will wait anxiously for them to come out of the oven and cool so they can enjoy them. There is just something that makes them taste so much better. Just like humans, our pups love fresh homemade treats and cookies! Our dogs are part of the family and we love to spoil them. They DO contain parsley which is a natural breath freshener and what self-respecting pup doesn’t want fresher breath?! What better way to spoil our best friends than with this easy Homemade Dog Biscuit recipe? These woofalicious dog biscuits require very few ingredients and are super easy to make. ![]() ![]() ![]() ![]() Manning's 26-touchdown, 15-interception season earned him Pro Bowl honors. His reputation of late-game heroics started here, as he posted six fourth-quarter comebacks and seven game-winning drives. In many respects, Peyton Manning's legend began during his sophomore campaign in 1999.įollowing a rough 1998 rookie season, during which his Indianapolis Colts finished 3-13, Manning made one of the greatest single-season turnarounds by leading his Colts to a 13-3 record in 1999. The Sheriff is regarded by most as one of the best quarterbacks in the game's history, and perhaps the greatest if you're asking those down south. His superlative 2017 season has Eagles fans thinking they have an all-time great on their hands, so how does it match up so far against some of the greats' second seasons as starters? We picked a select six and pulled statistics from Pro Football Reference to compare them with Wentz. No quarterback in NFL history has ever had such a season. Wentz is on pace for 4,200 yards, 38 touchdowns, nine interceptions and 400 rushing yards. He's made an NFL-record 540 completions through his first 24 games, and the projections for this season are record-breaking as well. He became just the eighth quarterback in history with 17 or more touchdowns along with four picks or fewer through seven games and is the first Eagles QB since 1953 to post three successive games with three or more touchdown tosses. ![]() Wentz's 2017 season is quickly becoming historic. He's the league co-leader in touchdown passes, with 19, and only has five interceptions, nipping at the heels of MVP favorite Tom Brady before Week 8 with 3-1 odds to win the award, per Justin Hartling of OddsShark. Second-year quarterback Carson Wentz is dominating game in and game out while leading the Philadelphia Eagles to the NFL's best record, and it beckons an inquiry into how his sophomore season matches up with some quarterback greats.Įvery team in the league is looking up at the high-flying Eagles, who sit at 7-1 thanks in large part to Wentz's brilliance. ![]() ![]() ![]() This however is speculative as we would have to see the SAS logs to see what it is reporting.Enabling JavaScript and cookies in your web browser ![]() ![]() I think that SuperAnti-Spyware is scaring you unnecessarily, as much of what it finds is cr4p, it really makes a big deal out of tracking cookies and they are not a security issue but a mildly privacy one. Your biggest problem is, A) identifying the type of RAM you have and B) sourcing the same specification of RAM. ![]() RAM is relatively cheap and even adding 1GB more can make a big difference. Me, I found real RAM is the only way to increase performance, so I have 4GB on this win XP Pro system the maximum it can handle. Basically I used a custom setting of it, more to stop it growing to big and becoming fragmented. I have modified my Virtual Memory and in all honesty it never made a blind bit of difference or you would probably need a stopwatch to see any difference (see attached image). This swapping in and out adds an additional load on the system and depending on your hard drive, it could be very slow and this is often the bottleneck on your system. If any information previously in RAM that is needed again it has to be swapped back in to RAM and this also means something is likely to have to be swapped out. This using Hard Disk space as Virtual RAM is never going to be as fast as normal RAM, this pagefile.sys has been used by default for some considerable time even in XP.Įssentially this just swaps out data in the Real RAM if it hasn't been accessed for a while and places it in the pagefile.sys, freeing up some real RAM space. So, I am guessing that this could also be causing the computer to slow down.ĭoes any of this make any sense? I feel like a real dumb bell not knowing any of this stuff! Then, at the end of the Smart Scan, I am told that I have issues with my network, and that I have 21 pieces of "Junk" that need to be removed, but that in order for me to remove it I need to upgrade to one of the other Avast products. I'm assuming that, when I run a scan with Avast, and none of the Ad.ware comes up during the Avast scan, that the ad.ware isn't that much of a threat, so Avast doesn't mess with it, but then, I don't know, not being computer savvy. Here is the video: Īnyway.I thought that maybe if I tried essexboys suggestion and add sme more RAM, that this might help.Īlso, I am using a program called "Super Anti Spyware Free Edition", and for some reason when I run a scan(which I am forced to do several times throughout the day) a bunch of Ad.ware, and once in awhile some serious malware comes up during the scan that needs to be removed. I was trying to follow along with this one, but had a hard time since the person isn't using XP, and when he got to the point where he uses the calculator-I was totally lost. Well.I was provided with a couple links to You Tube videos on how to add RAM by taking it from the actuall Hard Drive. I am on a fixed income (Yes, I'm a dinosaur ) and have to search for as much "free" stuff when it comes to my 10 year old PC as I can get. I Googles "How to I boost my RAM for free?". However, I am STILL having problems with my computer being too slow, and it is now running even slower than it was before, which makes me wonder if I couldn't have done something wrong, or, perhaps I just need to take the last step that essex provided me with, which was to get some more RAM, because things are really messed up in that department. I don't you know if you have been following the other thread I started last week, re: "Avast has messed up my computer"-but a forum member here, Essexboy, Schmidthouse, Gopher John and IXWolfe all gave me advice, and essexboy really helped me get things back to normal with Avast. The last thing I need is someone trying to sell me something. Thank you for that important and much appreciated info. ![]() ![]() ![]() You can visit our support site by following this link. Our support community would be more than happy to help with this. Our team is constantly working to improve our app and we appreciate your patience as we work to solve this issue. We apologize for the frustration you have experienced with your Apple Magic Keyboard and the address box. Thank you for taking the time to share your experience with our app. This is why I have given it 1 star, because at present it is unusable as a web browser in this configuration. The only reason it stays on the iPad at the moment, is that I am hoping one day they will fix this problem. This means that the web browser does not allow you to visit any webpages, or do anything. You can't even paste addresses into the address box. The window flashes quickly, but nothing happens, no I beam and no text entry capability. If you use an Apple Magic Keyboard on an iPad Pro, you are unable to enter any text in the address box. I've been hoping that over time the devs would have solved a simple problem, but alas this is not happening. The application automatically blocks many online trackers. (Free) User rating Download Latest Version for Android Privacy-focused browser 1/6 Firefox Focus is a mobile browser that ensures your privacy. Īfter several updates the software still does not work properly. Firefox Focus: The privacy browser APK for Android 114.2.0 Mozilla, Corp. We build products like Firefox to promote choice and transparency and give people more control over their lives online. Mozilla exists to build the Internet as a public resource accessible to all because we believe open and free is better than closed and controlled. Learn more about what’s up at Mozilla: Focus also blocks a wide range of trackers by default, including social trackers and those sticky ones that come from things like Facebook ads.įirefox Focus is backed by Mozilla, the non-profit that fights for your rights on the web, so you can trust it not to sell your data. Get to your favorite site even quicker without typing anything.įASTER BROWSING WITH AD BLOCKING & TRACKING PROTECTIONįirefox Focus blocks many ads you’d normally see on web pages so you get much faster page load speeds, which means you get to the stuff you want a lot faster. Pin up to four shortcuts on your home screen. ![]() Just a simple, minimal design with menus that make sense.Įrase your history, passwords and cookies with just a tap of the trash button. No recent history, no past sites, no open tabs, no ads, no distractions. When you open Focus, you just get the awesome bar and the keyboard for super quick searching. Firefox Focus is the perfect get in/get out, search and destroy, I’m on a mission that’s none-of-your-business - web browser. One tap, and your browsing history is completely destroyed.īlocking distracting ads also means faster page loads which means Focus gets you where you want to go a lot faster. Use Firefox Focus for everything you want to keep separate from your main browser - for all those get in get out and forget about it moments. ![]() ![]() ![]() With both versions, users have the option to burn their own audio cd for free using Burn Audio CD feature. The free version is FreeRIP Basic, and FreeRIP Pro is for paying users and offers advanced features such as multi-core optimization and the ability to run it at a higher priority, allowing the maximum speed possible. Pepsky Free Audio Converter is a helpful, free software only available for Windows. 313 8 Best Free Audio Converter Software Programs Converters for MP3, WAV, OGG, WMA, M4A, FLAC, and more By Tim Fisher Updated on JReviewed by Christine Baker An audio file converter is one kind of file converter that (surprise) is used to convert one type of audio file (like an MP3, WAV, WMA, etc.) into another type of audio file. FreeRIP can download track data from the famous, but also offers its exclusive FreeRIP CD DB which is a user-maintained database that offers a number of additional fields like lyrics, band, lyricist, etc.įreeRIP also offers advanced features such as the ability to rip multiple CD tracks to a single MP3 file, and a search shortcut menu to help you find images, videos, information and lyrics.ĭespite the huge number of functions it incorporates, FreeRIP has an intuitive user interface a toolbar with big icons and a main window divided into two parts, the first of which lists the tracks and the second part gives specific information on each track.įreeRIP natively supports multiple languages such as English, Italian, German, Spanish, Portuguese, French, etc., and users have the choice of two versions. Handy, fast audio player for MP3, OGG and Audio CD. Pepsky Free Audio Converter is a helpful, free software only available for Windows, belonging to. This free program is an intellectual property of Pepstyle International Limited. The Pepsky Free Music Converter installer is commonly called audioconverter.exe. Our antivirus check shows that this download is virus free. ![]() Pepsky Free Audio Converter is een handige, gratis software die alleen beschikbaar is voor Windows en behoort tot de categorie Audiosoftware met subcategorie Converters (meer specifiek MP3 WMA WAV OGG). Download Pepsky Free Music Converter 5.2.0.0 from our website for free. FreeRIP also integrates an MP3 tag editor that can handle both ID3 v1 and v2 tags, supports CD-Text and online CD databases for automatic metadata downloading. Multiformat audio-omzetter en audio-cd-brander voor MP3- en WMA-formaten. All you do is upload the original audio file (s), choose the desired output format, and then wait for the download button to appear. It is also an MP3 converter, so it can convert MP3 to WAV, OGG to MP3, WMA to MP3, WAV to FLAC, etc. This free audio converter service will convert most common audio formats, so long as they don't exceed 150 MB. FreeRIP is an easy-to-use Windows application that can convert audio from CD to MP3, OGG, FLAC, WAV and WMA. Download Pepsky Video Converter 7. Pepsky Free Audio Converter Pepsky Free Audio Converter là phn mm min phí bn có th chuyn i nh dng gia các files nhc, và save chúng li thành CD, hay các nh dng khác nh MP3, CD/DVD, WMA. ![]() ![]() ![]() And if shifted to NAV-based system, the holding value of EPFO should jump up by 20%- 30%. On a conservative estimate, the unrealised gains must be in the range of 20- 30%. Time for EPFO to shift to NAV based accounting The best time to convert to NAV-based scheme is now.Indian Railways gets ready for Accrual Accounting, its biggest such reform since Independence Railways is preparing financial statements for current fiscal under accrual-based accounting system, the process widely followed by the corporate sector.It helps give a better picture of the company's financial condition. Under the accrual method of accounting expenses are balanced with revenues on the income statement. The only drawback of this type of accounting system is that you, as a firm, might end up paying tax on revenues even when you might have not received it (credit). There is a possibility that you may not have received the payment by cash at that particular point in time.Īn expense is occurred or recorded when the raw material is ordered and not when the actual payment is made to the supplier by either cash or cheque. If you sell your goods or products on credit, the sale is recorded in the books based on the invoice generated. Here, any revenue or income which is generated by sales and expenses incurred are recorded as they occur. ![]() Suppose you are a firm M/S ABC Pvt Ltd, and you are using accrual accounting to maintain your books of accounts. Let's understand Accrual accounting with the help of an example. The use of accrual accounting is typically useful in businesses where there are a lot of credit transactions or the goods and services are sold on credit, which simply means that there was no exchange of cash. Accrual refers to an entry made in the books of accounts related to the recording of revenue or expense paid without any exchange of cash. This method is more appropriate in assessing the health of the organisation in financial terms.ĭescription: To understand accrual accounting, let's first understand what we mean when we say the word 'accrual'. ![]() Definition: When transactions are recorded in the books of accounts as they occur even if the payment for that particular product or service has not been received or made, it is known as accrual based accounting. ![]() ![]() ![]() Your physician will be able to assess your overall health and fitness, provide information and guidance on health risks you may encounter while traveling, medication you may need to take, and other precautions for the prevention of injury and illness during your program. It It is therefore your responsibility to consult with your physician and/or contact the CDC for health information specific to your travel destination. ![]() While Road Scholar does its best to provide pertinent information regarding international health requirements and travel health precautions for travel abroad, please remember we are not health experts and can only share with you the recommendations made by the CDC and the US Department of State. Department of State regarding their health condition and any recommendations specific to the destinations they will visit or transit well before departure. In addition to maintaining necessary vaccinations, including seasonal influenza vaccination, Road Scholar recommends all participants consult with their physician, the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and the U.S. To learn more about this plan, including its terms, conditions, limits, and exclusions, and to view and download a certificate of insurance, please visit: Travel Health This plan includes insurance benefits underwritten by Arch Insurance Company and emergency assistance services provided by LiveTravel Assist. This plan is purchased by Road Scholar on behalf of every participant. The plan provides 24-hour assistance in the event of an emergency during your program and insurance for emergency medical evacuation. Whether participating on a program in the United States or on one of our programs overseas, every Road Scholar participant receives coverage under the Road Scholar Assurance Plan. Road Scholar’s continued commitment to our participants and their well-being is exemplified in our Road Scholar Assurance Plan. Included Emergency Assistance and Medical Evacuation Insurance However, since individual circumstances vary, we suggest participants contact their tax advisors. The program price may qualify as a tax-deductible gift. ![]() Road Scholar and sponsoring service institutions are not-for-profit organizations and are tax-exempt under Section 501 (c)(3) of the Internal Revenue Code. Our Service Learning programs bring participants together to work as a team to serve worthy projects. We will discuss your request with you and make every effort to accommodate you. If you have special needs requiring accommodation, please communicate them to Road Scholar at the time of enrollment. Road Scholar is committed to providing reasonable accommodation to participants with special needs and disabilities. If you have special needs, or need a little extra help in finding the right program for your level of fitness and ambition, please call us and we’ll work to find options for you. Try our Advanced Search tool to find programs that match your activity level. Visit email us at or call us toll free at (877) 426-8056.Įach Road Scholar program is assigned an Activity Level rating, ranging from Easy Going to Challenging, which are noted on program webpages. Road Scholar offers two kinds of assistance: Scholarships, for those with desire but not the financial means to participate in our U.S.- or Canada-based learning adventures and Caregiver Grants, designed to provide a unique respite opportunity for unpaid family caregivers to participate in a U.S.- or Canada-based Road Scholar program. citizens are tax-deductible as provided by law. As Road Scholar is not a registered charity in Canada, donations are not tax deductible for Canadian citizens. Our Advisors are happy to explain this payment option to you.Īs a not-for-profit organization, we appreciate and rely on charitable donations to help us develop and maintain high-quality educational programs with exceptional value. Please consider our paperless check option when paying on the phone or over the Internet. Please help us reduce this cost by paying for your program with a check. Road Scholar is a not-for-profit 501 (c)(3) organization that incurs over $5 million annually on credit card fees. You may also enroll online at To reserve space on a program, Road Scholar requires a deposit followed by final payment. Please call us toll free at (877) 426-8056, Monday through Friday, 9 a.m. ![]() ![]() Immutep (known as Prima BioMed until November 2017) is an Australian clinical-stage biotechnology company that develops immunotherapies for cancer and autoimmune diseases. Given the encouraging overall survival data, IMM will continue to talk to regulators and potential partners about the development of efti in breast cancer the efti mBC programme in China should hopefully in any case move forwards. The ongoing TACTI-002 and -003 trials will continue to generate efti-PD-X combo data in HNSCC, where, with the right data, FDA Fast Track status could open the door to accelerated approval. Under threat from biosimilars, large pharma will be hungry for new products to protect and extend their proprietary markets few other PD-X combos have delivered, and the chemo combo is not sufficient to extend patents.įurther opportunities in solid cancers: While NSCLC will be the focus for Phase 3, IMM will continue to explore opportunities in HNSCC and mBC. With increased penetration from the substitution for chemo and triple therapy, we estimate that global peak revenues in NSCLC could reach $6.5bn, with Fast Track designation hoping to expedite this launch.Īpproaching PD-X patent expiry feed pharma appetite: Key patents are due to expire on PD-X products including pembrolizumab. NSCLC opportunity in excess of $6bn: The bulk of Merck's $17.2bn pembro revenues come from NSCLC. INSIGHT-003 is testing the additional first line impact of efti-PD-X-chemo triple therapy in NSCLC due to report first data Q4/2022E. Potential to expand responsive patient population: Safe and well tolerated, efti has already shown signs of synergy with chemo in the AIPAC Phase 2 in metastatic breast cancer ("mBC"). Avoiding the severe acute and long-term side effects, efti could provide an alternative to chemo for the majority of NSCLC patients. Pembro- efti combinations delivered a 42% overall response rate ("ORR") and 9.3-month median progression free survival ("mPFS") compared to 50% and 7.2 month with pembro-chemo SoC respectively. PD-X- chemo is the current 1st line SoC for 70% of late-stage NSCLC patients. Safer and better tolerated alternative to chemo: Governed by PD-L1 status, We reiterate both our OUTPERFORM recommendation and our AUD $2.00 target price. Financed to 2024E and with more data in the pipeline, IMM looks dramatically undervalued, in our view. The share price has been hit by market turbulence and flight from risk, but efti looks an attractive asset as PD-X patents expire. We anticipate efti total peak sales of at least $8bn valuing the company at c.AUD 1.7bn (AUD 2.03 / share). ![]() IMM has provided a constant flow of positive efti data across indications, including HNSCC and AIPAC metastatic breast ("mBC") phase 2b trial providing improvements in overall survival. Other perks can include Rolling Review, Accelerated Approval and Priority Review. Often speeding approvals, Fast Track takes IMM closer to the potential $6bn opportunity in NSCLC. Allowing for more frequent meetings with the FDA and streamlining the trial design and approval process, a welcome lift as IMM plan for phase 3 efti-pembro NSCLC trial. Through Fast Track designation FDA acknowledges the potential benefits of efti-pembro combo over existing therapies. Already with FDA Fast Track in head and neck cancer ("HNSCC"), the expedited review process was awarded based on the phase 2 data from the TACTI-002 study, indicating efti-PD-1 / L1 (PD-X) combinations could provide a safer and better tolerated alternative to the chemotherapy SoC in first line NSCLC, substantially expanding treatment responsive populations and decreasing toxicity-linked treatment discontinuation. FDA fast-tracks efti as chemo alternative in NSCLCįDA has granted Fast Track to eftilagimod alpha ("efti") in combination with Merck's anti-PD-1 therapy pembrolizumab ("pembro"), for first line treatment in NSCLC. ![]() |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |